HEPATITIS B FOUNDATION &
THE BARUCH S. BLUMBERG INSTITUTE
DISTINGUISHED SPEAKER SEMINAR
Integrated HBV DNA: Investigation of the Architecture and Potential Clinical Implications
Nicholas van Buuren, Ph.D.
Dr. Nicholas van Buuren is a Research Scientist in Clinical Virology at Gilead Science, Inc. He is the Biology lead of the Liver Biopsy Project which procures liver biopsies from patients with chronic hepatitis B virus infections, throughout the natural history of disease, and characterize the viral antigen burden, the liver immune microenvironment and the burden and architecture of integrated HBV DNA. Dr. van Buuren completed his BSc at the University of Victoria in 2003 in British Columbia, Canada with a major in Microbiology. He received his Ph.D. in 2012 in Medical Microbiology and Immunology at the University of Alberta, mentored by Dr. Michelle Barry. There he studied the complex interaction between poxviruses and their host and identified a family of Ankyrin/F-box proteins encoded by ectromelia virus that regulated the host ubiquitin-proteasome system. From 2017-2018 Dr. van Buuren was a Research Associate in the Department of Genetics at Stanford University, in the lab of Karla Kirkegaard, where he studied hepatitis C virus genetics in the context of drug resistance and characterized a phenomenon that the research team called the Dominant Drug Target.
Nicholas van Buuren